Dysarthric speech analysis and automatic recognition using phase based representations

Dysarthria is a neurological speech impairment which usually results in the loss of motor speech control due to muscular atrophy and poor coordination of articulators. Dysarthric speech is more difficult to model with machine learning algorithms, due to inconsistencies in the acoustic signal and to limited amounts of training data. This study reports a new approach for the analysis and representation of dysarthric speech, and applies it to improve ASR performance. The Zeros of Z-Transform (ZZT) are investigated for dysarthric vowel segments. It shows evidence of a phase-based acoustic phenomenon that is responsible for the way the distribution of zero patterns relate to speech intelligibility. It is investigated whether such phase-based artefacts can be systematically exploited to understand their association with intelligibility. A metric based on the phase slope deviation (PSD) is introduced that are observed in the unwrapped phase spectrum of dysarthric vowel segments. The metric compares the differences between the slopes of dysarthric vowels and typical vowels. The PSD shows a strong and nearly linear correspondence with the intelligibility of the speaker, and it is shown to hold for two separate databases of dysarthric speakers. A systematic procedure for correcting the underlying phase deviations results in a significant improvement in ASR performance for speakers with severe and moderate dysarthria. In addition, information encoded in the phase component of the Fourier transform of dysarthric speech is exploited in the group delay spectrum. Its properties are found to represent disordered speech more effectively than the magnitude spectrum. Dysarthric ASR performance was significantly improved using phase-based cepstral features in comparison to the conventional MFCCs. A combined approach utilising the benefits of PSD corrections and phase-based features was found to surpass all the previous performance on the UASPEECH database of dysarthric speech

Acute ischaemic stroke associated with SARS-CoV-2 infection in North America

BACKGROUND: To analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome. METHODS: Multicentre retrospective cohort study of COVID-19 patients with AIS who presented to 30 stroke centres in the USA and Canada between 14 March and 30 August 2020. The primary endpoint was poor functional outcome, defined as a modified Rankin Scale (mRS) of 5 or 6 at discharge. Secondary endpoints include favourable outcome (mRS ≤2) and mortality at discharge, ordinal mRS (shift analysis), symptomatic intracranial haemorrhage (sICH) and occurrence of in-hospital complications. RESULTS: A total of 216 COVID-19 patients with AIS were included. 68.1% (147/216) were older than 60 years, while 31.9% (69/216) were younger. Median [IQR] National Institutes of Health Stroke Scale (NIHSS) at presentation was 12.5 (15.8), and 44.2% (87/197) presented with large vessel occlusion (LVO). Approximately 51.3% (98/191) of the patients had poor outcomes with an observed mortality rate of 39.1% (81/207). Age \u3e60 years (aOR: 5.11, 95% CI 2.08 to 12.56, p\u3c0.001), diabetes mellitus (aOR: 2.66, 95% CI 1.16 to 6.09, p=0.021), higher NIHSS at admission (aOR: 1.08, 95% CI 1.02 to 1.14, p=0.006), LVO (aOR: 2.45, 95% CI 1.04 to 5.78, p=0.042), and higher NLR level (aOR: 1.06, 95% CI 1.01 to 1.11, p=0.028) were significantly associated with poor functional outcome. CONCLUSION: There is relationship between COVID-19-associated AIS and severe disability or death. We identified several factors which predict worse outcomes, and these outcomes were more frequent compared to global averages. We found that elevated neutrophil-to-lymphocyte ratio, rather than D-Dimer, predicted both morbidity and mortality

Report of the Topical Group on Cosmic Probes of Dark Matter for Snowmass 2021

Cosmological and astrophysical observations currently provide the only robust, positive evidence for dark matter. Cosmic probes of dark matter, which seek to determine the fundamental properties of dark matter through observations of the cosmos, have emerged as a promising means to reveal the nature of dark matter. This report summarizes the current status and future potential of cosmic probes to inform our understanding of the fundamental nature of dark matter in the coming decade.Comment: Report of the CF3 Topical Group for Snowmass 2021; 35 pages, 10 figures, many references. V3 updates Fig 3-2 and the author lis

Rights and Duties of Broadcasting Organizations: Analysis of WIPO Treaty on the Protection of Broadcasting Organizations

402-408Transmission of data through a signal based approach has been made possible by the broadcasting organizations, but it has come at certain costs. The problem posed by incidences of signal theft induced the member states of World Intellectual Property Organization to create a new international tool in the form of a treaty to tackle this problem. The paper seeks to analyse this in the light of present legal regime where protection is granted to the broadcasting organizations, and whether granting further protection in the form of exclusive rights will serve the interest of developing nations or not. The representatives of developing nations have made it clear that if the treaty is not based on elementary and absolutely necessary rights, it should be abandoned. A study of the treaty makes it clear that the primary purpose of treaty is not to tackle signal theft, which makes its primary agenda ancillary in nature

Fast vocabulary learning for disordered speech vocal interfaces

Gemmeke J.F., Sehgal S., Cunningham S., ''Fast vocabulary learning for disordered speech vocal interfaces'', Technical report KUL/ESAT/PSI/1403, KU Leuven, ESAT, April 2014, Leuven, Belgium.status: publishe